Endocrine Abstracts

Introduction: Central diabetes insipidus (CDI) is a rare but potentially dangerous dysregulation of the water balance secondary to an arginine vasopressin (AVP) deficiency. Diabetes insipidus may have different manifestations in children compared to adults. CDI is more common in children than nephrogenic diabetes insipidus.Methods: A retrospective study of eight patients collected in the pediatric department of Mahdia.Results: The ...

Introduction: It is because of the heavy somatic and especially intellectual impact of congenital hypothyroidism that its systematic screening from birth has been proved to be essential. Numerous publications have already reported the considerable improvement in the prognosis of this condition but still few relate to adults. This preliminary work proposes to report the adult outcome in a cohort of 12 patients followed for congenital hypothyroidism.Patien...

Introduction: Congenital hypothyroidism is 30 times more frequent in newborns with Down syndrome (DS) than in the population of healthy children. Mild isolated TSH elevation with normal thyroxine (T4) levels is the most commonly seen pattern of thyroid dysfunction in these children.Patients and methods: A retrospective study was carried out on eleven patients with DS in the pediatric department of Mahdia who were followed for congenital hypothyroidism.</...

Introduction: Many problems hinder the diagnostic and therapeutic approach of growth hormone deficiency (GHD) in developing countries. The lack of early diagnosis and adequate treatment have adverse consequences, especially the small final height with the resulting psychological impact. Our study examined 40 cases of GHD who received treatment by recombinant human Growth Hormone (rhGH).Patients and methods: This is a retrospective longitudinal study of 4...

Introduction: GH deficiency (GHD) is a rare etiology of late growth. Its exact prevalence is unknown in emerging countries such as Tunisia. Despite a very suggestive clinical presentation, the diagnosis of GHD remains difficult and relatively late in some patients. Our study examined 40 cases of GHD in the Sahel region of Tunisia.Patients and methods: This is a retrospective longitudinal study of 40 cases of GHD collected in the pediatric department of M...